N-3 Polyunsaturated Fatty Acids, Body Fat and Inflammation

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N-3 Polyunsaturated Fatty Acids, Body Fat and Inflammation

BACKGROUND Based on animal studies, n-3 polyunsaturated fatty acids (PUFAs) have been suggested to lower the risk of obesity and inflammation. We aimed to investigate if, among humans, intake of n-3 PUFAs was associated with i) total body fat, ii) body fat distribution and iii) obesity-related inflammatory markers. METHODS The study population consisted of 1,212 healthy individuals with infor...

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n-3 Polyunsaturated fatty acids, inflammation and obesity-related disease.

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n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases.

Inflammation is part of the normal host response to infection and injury. However, excessive or inappropriate inflammation contributes to a range of acute and chronic human diseases and is characterized by the production of inflammatory cytokines, arachidonic acid-derived eicosanoids (prostaglandins, thromboxanes, leukotrienes, and other oxidized derivatives), other inflammatory agents (e.g., r...

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n-3 polyunsaturated fatty acids and cancer.

n-3 Polyunsaturated fatty acids are promising molecules in cancer prevention and the potentiation of cancer treatment. Recent studies have highlighted the importance of their interactions with other food components. Their effects on tumor growth depend upon background levels of n-6 polyunsaturated fatty acids and antioxidants, and this could account for previously inconsistent results in experi...

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Polyunsaturated fatty acids and inflammation.

The n-6 polyunsaturated fatty acid, arachidonic acid, is a precursor of prostaglandins, leukotrienes and related compounds that have important roles as mediators and regulators of inflammation. Consuming increased amounts of long chain n-3 polyunsaturated fatty acids (found in oily fish and fish oils) results in a partial replacement of the arachidonic acid in cell membranes by eicosapentaenoic...

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ژورنال

عنوان ژورنال: Obesity Facts

سال: 2013

ISSN: 1662-4033,1662-4025

DOI: 10.1159/000354663